Wednesday 22 February 2012

The Return of the Genes

After discredited, gene therapy saves patients with AIDS and cancer

Editora Globo
HELP FROM THE ENEMY: Scientists from France prepare bacteria and viruses to carry genes
Called revolutionary in the 90s and lost hope after killing a voluntary testing in 1999, gene therapy will reappear with adjectives and less impacting more significant results. "In the last two decades, more than 1500 clinical trials were conducted and 5000 persons have experienced the therapy," says biochemist Sang Won Han, USP. This new group of tests brought for the first time, improvement in conditions gene (causing bleeding from blindness), and also in cases of cancer cure observation. "Until then, treat patients with genetic ills was just science fiction."

The modified virus treatment is used to carry therapeutic genes to target cells. "There are vectors [as it is called this transportation] available to treat some types of cancer. In the future, it is expected that others are for sale, "said Won Han. "Researchers have turned their attention to cardiovascular or infectious diseases," said Marcial Francis Galera, president of the Brazilian Society of Medical Genetics. The most successful is the U.S. executive Timothy Ray Brown, 45 years. Underwent a bone marrow transplant in 2007, he never showed signs of that, one day, as was HIV positive. "Some genetic transfers do not work as they should and others can be dangerous. But gene therapy is already considered a hope of cure for AIDS, "says the German hematologist Gero Hütter, responsible for the case of Brown.



Source Galileu.

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